[Micrometric and morphological assessment of early stage rat embryos -- application for in vivo teratology testing]

Ginekol Pol. 1998 Dec;69(12):919-22.
[Article in Polish]

Abstract

Authors presented the whole embryo culture (WEC) method suggested for embryotoxicity study. The present paper concentrates on morphological scoring system proposed by Brown and Fabro in 1981. The scoring system provides a precise index of embryonic development and allows a quantitative comparison of development and growth. In our study we used this system with slight modification for assessing an 86 control rat embryos. We have found that routine use of this scoring system in teratology embryo culture experiments may afford further benefits.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Embryo, Mammalian / chemistry*
  • Embryo, Mammalian / cytology*
  • Embryonic and Fetal Development
  • Female
  • Pregnancy
  • Pregnancy, Animal / physiology*
  • Rats
  • Rats, Wistar / embryology
  • Teratogens / analysis*
  • Time Factors

Substances

  • Teratogens