Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma: a phase I/II study

J Mol Med (Berl). 1999 Apr;77(4):393-8. doi: 10.1007/s001090050366.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Clinical Trial, Phase II

MeSH terms

  • Adult
  • Aged
  • Cell Line
  • Cytochrome P-450 CYP2B1 / administration & dosage*
  • Cytochrome P-450 CYP2B1 / genetics*
  • Drug Compounding*
  • Female
  • Genetic Therapy*
  • Genetic Vectors
  • Humans
  • Ifosfamide / administration & dosage
  • Ifosfamide / pharmacology*
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / therapy*
  • Transfection*

Substances

  • Cytochrome P-450 CYP2B1
  • Ifosfamide