Combined sentinel lymph-node mapping and bone-marrow micrometastatic analysis for improved staging in breast cancer

Lancet. 1999 Jul 10;354(9173):129-30. doi: 10.1016/s0140-6736(99)02664-1.

Abstract

In a prospective study of 29 patients with clinically node-negative breast cancer, sampling of rib marrow was superior to sampling of iliac-crest marrow for detection of micrometastases. Combination of marrow micrometastatic analysis with sentinel lymph-node mapping may improve accuracy of staging in breast cancer.

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Axilla
  • Bone Marrow Neoplasms / pathology
  • Bone Marrow Neoplasms / secondary*
  • Breast Neoplasms / pathology*
  • Female
  • Humans
  • Ilium
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis / diagnosis
  • Neoplasm Staging / methods*
  • Prospective Studies
  • Ribs / pathology