Synthesis of new PMEA diphosphate mimics

Nucleosides Nucleotides. 1999 Apr-May;18(4-5):1003-4. doi: 10.1080/15257779908041629.

Abstract

We synthesized and characterized new diphosphate mimics of the acyclic nucleoside phosphonate PMEA [Adefovir, 9-(2-phosphonylmethoxyethyl)adenine].

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenine / analogs & derivatives*
  • Adenine / chemical synthesis
  • Adenine / chemistry
  • Antiviral Agents / chemical synthesis*
  • Antiviral Agents / chemistry
  • Chromatography, Ion Exchange
  • Organophosphonates*
  • Organophosphorus Compounds / chemical synthesis

Substances

  • Antiviral Agents
  • Organophosphonates
  • Organophosphorus Compounds
  • adefovir
  • Adenine