Bactericidal/permeability-increasing protein inhibits growth of a strain of Acholeplasma laidlawii and L forms of the gram-positive bacteria Staphylococcus aureus and Streptococcus pyogenes

Antimicrob Agents Chemother. 1999 Sep;43(9):2314-6. doi: 10.1128/AAC.43.9.2314.

Abstract

Bactericidal/permeability-increasing protein (BPI) inhibited growth of cell wall-deficient Acholeplasma laidlawii and L forms of certain strains of Staphylococcus aureus and Streptococcus pyogenes. However, the same strains of S. aureus and S. pyogenes with intact cell walls were not susceptible to the growth-inhibitory effects of BPI.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acholeplasma laidlawii / drug effects*
  • Acholeplasma laidlawii / growth & development
  • Anti-Bacterial Agents / pharmacology*
  • Antimicrobial Cationic Peptides
  • Blood Proteins / pharmacology*
  • Membrane Proteins*
  • Staphylococcus aureus / classification
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / growth & development
  • Streptococcus pyogenes / classification
  • Streptococcus pyogenes / drug effects*
  • Streptococcus pyogenes / growth & development

Substances

  • Anti-Bacterial Agents
  • Antimicrobial Cationic Peptides
  • Blood Proteins
  • Membrane Proteins
  • bactericidal permeability increasing protein