Relation between infarct artery patency at late angiography after acute myocardial infarction and signal-averaged electrocardiography

Am J Cardiol. 1999 Sep 15;84(6):734-6, A8. doi: 10.1016/s0002-9149(99)00423-3.

Abstract

The angiograms of 89 patients were reviewed from the LATE Ancillary Study (randomized trial of recombinant tissue plasminogen activator vs placebo in patients with symptom onset after 6 hours of myocardial infarction) to determine patency of the infarct-related artery (IRA). In the occluded IRA group (n = 35), the incidence of signal-averaged electrocardiographic abnormality (fQRS > 120 ms) was significantly higher (p = 0.04), the filtered QRS duration was significantly longer (p = 0.007), and the V40 was significantly shorter (p = 0.02), compared with the patent IRA group (n = 54).

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Coronary Angiography* / drug effects
  • Death, Sudden, Cardiac / etiology
  • Death, Sudden, Cardiac / prevention & control
  • Electrocardiography* / drug effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / drug therapy*
  • Myocardial Infarction / mortality
  • Prospective Studies
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Signal Processing, Computer-Assisted*
  • Thrombolytic Therapy*
  • Tissue Plasminogen Activator / therapeutic use*
  • Ventricular Fibrillation / diagnosis
  • Ventricular Fibrillation / drug therapy
  • Ventricular Fibrillation / mortality

Substances

  • Tissue Plasminogen Activator