Digoxin and mortality in chronic heart failure. UK Heart Investigation

Lancet. 1999 Sep 18;354(9183):1003. doi: 10.1016/s0140-6736(99)03815-5.

Abstract

Data from recent clinical trials suggest digoxin is now widely used in patients with chronic heart failure in sinus rhythm. We present data from a heart failure registry that reiterates concerns about the safety of digoxin in this population.

Publication types

  • Letter

MeSH terms

  • Cardiotonic Agents / adverse effects*
  • Cardiotonic Agents / therapeutic use
  • Digoxin / adverse effects*
  • Digoxin / therapeutic use
  • Heart Failure / drug therapy*
  • Heart Failure / mortality*
  • Humans
  • Proportional Hazards Models
  • Prospective Studies
  • Registries / statistics & numerical data
  • Retrospective Studies

Substances

  • Cardiotonic Agents
  • Digoxin