Not so slowly progressive visual loss

Surv Ophthalmol. 1999 Nov-Dec;44(3):247-52. doi: 10.1016/s0039-6257(99)00099-5.

Abstract

A 51-year-old man presented with bilateral progressive visual loss during a 2-month period. Visual acuity was 20/60 in both eyes with bilateral constricted visual fields. Funduscopy revealed bilateral disk pallor and arteriolar attenuation. His vision declined rapidly during the next 2 weeks. Investigations showed a positive cerebrospinal fluid Venereal Disease Research Laboratory test (1:8). A diagnosis of neurosyphilis was made, and treatment was started with high-dose intravenous and intramuscular penicillin.

Publication types

  • Case Reports
  • Clinical Conference

MeSH terms

  • Antibodies, Bacterial / cerebrospinal fluid
  • Cerebrospinal Fluid / immunology
  • Cerebrospinal Fluid / microbiology
  • Disease Progression
  • Electroretinography
  • Humans
  • Male
  • Middle Aged
  • Neurosyphilis / diagnosis*
  • Neurosyphilis / drug therapy
  • Neurosyphilis / physiopathology
  • Penicillins / therapeutic use
  • Treponema Immobilization Test
  • Treponema pallidum / immunology
  • Vision Disorders / diagnosis*
  • Vision Disorders / drug therapy
  • Vision Disorders / physiopathology
  • Visual Acuity
  • Visual Fields

Substances

  • Antibodies, Bacterial
  • Penicillins