Childhood trauma and dissociative symptoms in panic disorder

Am J Psychiatry. 2000 Mar;157(3):451-3. doi: 10.1176/appi.ajp.157.3.451.

Abstract

Objective: Childhood trauma has been associated with increased risk for both panic disorder and dissociative symptoms in adulthood. The authors hypothesized that among individuals with a primary diagnosis of panic disorder, those experiencing depersonalization/derealization during panic attacks would be more likely to have a history of childhood trauma.

Method: Rates of traumatic events were compared between panic disorder patients with (N=34) and without (N=40) prominent depersonalization/derealization during panic attacks. Symptom severity in the two groups was also examined.

Results: Contrary to the authors' hypothesis, no evidence was found that depersonalization/derealization during panic attacks was associated with childhood trauma. Minimal differences in severity of illness were found between patients with dissociative symptoms and those without such symptoms.

Conclusions: This finding is consistent with a multifactorial model of dissociation. Factors other than childhood trauma and general psychopathology may underlie vulnerability to dissociative symptoms in panic disorder.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulatory Care
  • Child Abuse / diagnosis
  • Child Abuse / statistics & numerical data*
  • Child Abuse, Sexual / diagnosis
  • Child Abuse, Sexual / statistics & numerical data
  • Comorbidity
  • Depersonalization / diagnosis
  • Depersonalization / epidemiology
  • Depersonalization / psychology
  • Diagnosis, Differential
  • Dissociative Disorders / diagnosis*
  • Dissociative Disorders / epidemiology
  • Dissociative Disorders / psychology
  • Humans
  • Life Change Events*
  • Middle Aged
  • Panic Disorder / diagnosis*
  • Panic Disorder / epidemiology
  • Panic Disorder / psychology
  • Severity of Illness Index