Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome?

Leukemia. 2000 May;14(5):943-4. doi: 10.1038/sj.leu.2401753.
No abstract available

Publication types

  • Comment
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Agents / toxicity*
  • Blast Crisis
  • Cell Survival / drug effects*
  • Child
  • Cytarabine / toxicity
  • Dexamethasone / toxicity
  • Down Syndrome / complications*
  • Doxorubicin / toxicity
  • Etoposide / toxicity
  • Humans
  • Leukemia, Myeloid, Acute / complications*
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / pathology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Thioguanine / toxicity
  • Treatment Outcome
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Cytarabine
  • Etoposide
  • Dexamethasone
  • Doxorubicin
  • Thioguanine