Supplementary motor area activation preceding voluntary movement is detectable with a whole-scalp magnetoencephalography system

Neuroimage. 2000 Jun;11(6 Pt 1):697-707. doi: 10.1006/nimg.2000.0579.

Abstract

Despite the fact that the knowledge about the structure and the function of the supplementary motor area (SMA) is steadily increasing, the role of the SMA in the human brain, e.g., the contribution of the SMA to the Bereitschaftspotential, still remains unclear and controversial. The goal of this study was to contribute further to this discussion by taking advantage of the increased spatial information of a whole-scalp magnetoencephalography (MEG) system enabling us to record the magnetic equivalent of the Bereitschaftspotential 1, the Bereitschaftsfeld 1 (BF 1) or readiness field 1. Five subjects performed a complex, and one subject a simple, finger-tapping task. It was possible to record the BF 1 for all subjects. The first appearance of the BF 1 was in the range of -1.9 to -1.7 s prior to movement onset, except for the subject performing the simple task (-1 s). Analysis of the development of the magnetic field distribution and the channel waveforms showed the beginning of the Bereitschaftsfeld 2 (BF 2) or readiness field 2 at about -0.5 s prior to movement onset. In the time range of BF 1, dipole source analysis localized the source in the SMA only, whereas dipole source analysis containing also the time range of BF 2 resulted in dipole models, including dipoles in the primary motor area. In summary, with a whole-head MEG system, it was possible for the first time to detect SMA activity in healthy subjects with MEG.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Contingent Negative Variation / physiology
  • Fingers / physiology
  • Humans
  • Magnetoencephalography / methods*
  • Male
  • Motor Cortex / physiology*
  • Movement / physiology*
  • Muscle, Skeletal / physiology*
  • Reference Values
  • Scalp