A case of cutaneous reaction to chemotherapeutic agents showing epidermal dysmaturation

Y S Chun; S N Chang; D Oh; W H Park

doi:10.1067/mjd.2000.101589

A case of cutaneous reaction to chemotherapeutic agents showing epidermal dysmaturation

J Am Acad Dermatol. 2000 Aug;43(2 Pt 2):358-60. doi: 10.1067/mjd.2000.101589.

Authors

Y S Chun¹, S N Chang, D Oh, W H Park

Affiliation

¹ Departments of Dermatology and Internal Medicine, College of Medicine Pochon CHA University, Seoul, Korea.

PMID: 10901723
DOI: 10.1067/mjd.2000.101589

Abstract

Cutaneous chemotherapy reactions are more likely to be toxic than allergic. Epidermal dysmaturation refers to histologic changes that may be observed in the epidermis after any significant cytoreductive therapy. We report a case of epidermal dysmaturation occurring in a patient with acute myelogenous leukemia after antineoplastic chemotherapy.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Cell Differentiation / drug effects
Drug Eruptions / diagnosis*
Drug Eruptions / pathology
Humans
Keratinocytes / drug effects
Keratinocytes / pathology
Leukemia, Myeloid, Acute / drug therapy*
Male
Skin / drug effects
Skin / pathology
Skin Diseases, Papulosquamous / chemically induced*
Skin Diseases, Papulosquamous / pathology