Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease

Am J Geriatr Psychiatry. 2000 Summer;8(3):254-6.

Abstract

The authors compared Apo-E epsilon 4 frequencies for Cuban American and white non-Hispanic persons with and without Alzheimer's disease (AD). The Apo-E epsilon 4 allele conferred as large a risk for AD in Cuban Americans as for white non-Hispanics, a finding that differs from those for Hispanic subjects as a whole.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Alleles
  • Alzheimer Disease / ethnology*
  • Alzheimer Disease / genetics*
  • Apolipoprotein E4
  • Apolipoproteins E / genetics*
  • Case-Control Studies
  • Cuba / ethnology
  • Female
  • Florida
  • Genotype
  • Hispanic or Latino / genetics*
  • Humans
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • White People / genetics

Substances

  • Apolipoprotein E4
  • Apolipoproteins E