Efficacy of rilmenidine, a selective I1 imidazoline receptor binding agent in diabetic hypertensive patients

Am J Hypertens. 2000 Jun;13(6 Pt 2):123S-126S. doi: 10.1016/s0895-7061(00)00227-2.

Abstract

Hypertension is a frequent complication in diabetes, and microalbuminuria has become an essential index of cardiovascular prognosis in type 2 diabetics. The pilot study reported here shows that rilmenidine, in addition to its antihypertensive action and good clinical tolerability, has the further advantage of reducing microalbuminuria, similar to captopril.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / metabolism*
  • Antihypertensive Agents / therapeutic use*
  • Clinical Trials as Topic
  • Diabetic Angiopathies / drug therapy*
  • Humans
  • Hypertension / drug therapy*
  • Imidazoline Receptors
  • Oxazoles / metabolism*
  • Oxazoles / therapeutic use*
  • Receptors, Drug / metabolism*
  • Rilmenidine

Substances

  • Antihypertensive Agents
  • Imidazoline Receptors
  • Oxazoles
  • Receptors, Drug
  • imidazoline I1 receptors
  • Rilmenidine