Clinical consequences of defects in the IL-12-dependent interferon-gamma (IFN-gamma) pathway

Clin Exp Immunol. 2000 Sep;121(3):417-25. doi: 10.1046/j.1365-2249.2000.01284.x.

Authors

D A Lammas¹, J L Casanova, D S Kumararatne

Affiliation

¹ MRC Centre for Immune Regulation, The Medical School and Regional Department of Immunology, Heartlands Hospital, Birmingham, UK.

No abstract available

Publication types

Review

MeSH terms

Animals
Bacterial Infections / etiology
Bacterial Infections / genetics
Bacterial Infections / immunology
Humans
Immunologic Deficiency Syndromes / etiology
Immunologic Deficiency Syndromes / genetics
Immunologic Deficiency Syndromes / immunology
Interferon gamma Receptor
Interferon-gamma / genetics*
Interferon-gamma / physiology*
Interleukin-12 / deficiency
Interleukin-12 / genetics
Interleukin-12 / physiology*
Prognosis
Receptors, Interferon / deficiency
Receptors, Interferon / genetics
Receptors, Interferon / physiology
Receptors, Interleukin / deficiency
Receptors, Interleukin / genetics
Receptors, Interleukin / physiology
Receptors, Interleukin-12
Signal Transduction
Th1 Cells / immunology
Th2 Cells / immunology

Substances

Receptors, Interferon
Receptors, Interleukin
Receptors, Interleukin-12
Interleukin-12
Interferon-gamma