Rapid development of Epstein-Barr virus-associated Hodgkin's disease after cessation of foscarnet therapy in an HIV-infected patient

Int J STD AIDS. 2000 Sep;11(9):609-10. doi: 10.1258/0956462001916489.

Abstract

Epidemiological features suggest a link between Hodgkin's disease (HD) and Epstein-Barr virus (EBV) infection. Indeed, EBV genome and expression of latent antigens can be found in Reed-Sternberg cells. In the majority of cases HD in HIV patients seems to be EBV-associated. We report on a 51-year-old HIV-infected patient in whom EBV-positive HD of mixed cellularity rapidly developed within one month after cessation of treatment with intravenous foscarnet.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / administration & dosage
  • Antiviral Agents / therapeutic use*
  • Epstein-Barr Virus Infections / etiology*
  • Epstein-Barr Virus Infections / prevention & control
  • Foscarnet / administration & dosage
  • Foscarnet / therapeutic use*
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • Hodgkin Disease / etiology*
  • Hodgkin Disease / prevention & control
  • Hodgkin Disease / virology
  • Humans
  • Male
  • Middle Aged

Substances

  • Antiviral Agents
  • Foscarnet