[Correction by common sea buckthorn bark and sprout extracts of hormonal and metabolic disturbances during stress in rats]

Eksp Klin Farmakol. 2000 Jul-Aug;63(4):70-3.
[Article in Russian]

Abstract

Long-term administration of the common sea buckthorn bark and sprout extract improves the hormonal-metabolic organism status in rats disturbed by a stress factor (immobilization). The drug administration led to normalization of the altered functional activity indices of the neuro-endocrine system (disturbed adrenocorticotropin, 11-deoxycortisol, insulin, urea, and glucose levels) by affecting the production of glucocorticoids and increasing the hypothalamus sensitivity with respect to regulatory signals.

Publication types

  • English Abstract

MeSH terms

  • Adrenocorticotropic Hormone / metabolism
  • Adrenocorticotropic Hormone / pharmacology
  • Animals
  • Blood Glucose / metabolism
  • Cortodoxone / blood
  • Dexamethasone / pharmacology
  • Homeostasis
  • Hormones / metabolism*
  • Hypothalamo-Hypophyseal System / drug effects
  • Insulin / blood
  • Pituitary-Adrenal System / drug effects
  • Plant Extracts / therapeutic use*
  • Plant Stems / chemistry
  • Rats
  • Rats, Wistar
  • Stress, Physiological / drug therapy*
  • Stress, Physiological / metabolism
  • Urea / blood

Substances

  • Blood Glucose
  • Hormones
  • Insulin
  • Plant Extracts
  • Dexamethasone
  • Urea
  • Adrenocorticotropic Hormone
  • Cortodoxone