New acetylenic compounds from the stony coral Montipora sp

B H Bae; K S Im; W C Choi; J Hong; C O Lee; J S Choi; B W Son; J I Song; J H Jung

doi:10.1021/np0002076

New acetylenic compounds from the stony coral Montipora sp

J Nat Prod. 2000 Nov;63(11):1511-4. doi: 10.1021/np0002076.

Authors

B H Bae¹, K S Im, W C Choi, J Hong, C O Lee, J S Choi, B W Son, J I Song, J H Jung

Affiliation

¹ College of Pharmacy, Pusan National University, Pusan 609-735, Korea.

PMID: 11087594
DOI: 10.1021/np0002076

Abstract

Six new acetylenic compounds (1-6) with cytotoxic activities against human solid tumor cell lines (SK-OV-3, SK-MEL-2, XF498, and HCT15) have been isolated from the stony coral Montipora sp. Structures of the compounds 1-6 were elucidated based on analysis of the NMR and MS data.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents / isolation & purification*
Antineoplastic Agents / pharmacology
Artemia
Chromatography, High Pressure Liquid
Cnidaria / chemistry*
Drug Screening Assays, Antitumor
Fatty Acids, Unsaturated / isolation & purification*
Fatty Acids, Unsaturated / pharmacology
Humans
Korea
Magnetic Resonance Spectroscopy

Substances

Antineoplastic Agents
Fatty Acids, Unsaturated