Comparison between strategies using creatine kinase-MB(mass), myoglobin, and troponin T in the early detection or exclusion of acute myocardial infarction in patients with chest pain and a nondiagnostic electrocardiogram

Am J Cardiol. 2000 Dec 15;86(12):1367-71, A5. doi: 10.1016/s0002-9149(00)01245-5.

Abstract

Different strategies using creatine kinase-MB(mass), myoglobin, and troponin T were compared in 738 patients admitted because of chest pain and an electrocardiogram not diagnostic of acute myocardial infarction. We conclude that a combination of creatine kinase-MB and troponin T during the first 6 hours enables early detection or exclusion of acute myocardial infarction in this population.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Angina Pectoris / blood
  • Angina Pectoris / diagnosis*
  • Angina, Unstable / blood
  • Angina, Unstable / diagnosis
  • Area Under Curve
  • Creatine Kinase / blood*
  • Creatine Kinase, MB Form
  • Diagnosis, Differential
  • Electrocardiography*
  • Female
  • Humans
  • Isoenzymes / blood*
  • Male
  • Myocardial Infarction / blood
  • Myocardial Infarction / diagnosis*
  • Myoglobin / blood*
  • Predictive Value of Tests
  • Prognosis
  • ROC Curve
  • Sensitivity and Specificity
  • Time Factors
  • Troponin T / blood*

Substances

  • Isoenzymes
  • Myoglobin
  • Troponin T
  • Creatine Kinase
  • Creatine Kinase, MB Form