The role of sentinel lymph nodes in malignant melanoma

Surg Clin North Am. 2000 Dec;80(6):1741-57. doi: 10.1016/s0039-6109(05)70258-9.

Abstract

Selective sentinel lymph node dissection should be considered a standard approach in the treatment of primary malignant melanoma. With the combination of blue dye and radioisotope mapping, the sentinel lymph nodes (SLNs) can be harvested with pinpoint accuracy. This article compares blue dye and radioisotope mapping techniques. Based on the clinical outcome data of selective sentinel lymph node dissection, micrometastasis to the SLNs carries a poor prognosis for patients with primary invasive melanoma.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Coloring Agents
  • Humans
  • Lymphatic Metastasis / pathology*
  • Melanoma / mortality
  • Melanoma / pathology*
  • Melanoma / surgery
  • Predictive Value of Tests
  • Prognosis
  • Radioisotopes
  • Reproducibility of Results
  • Risk Factors
  • Rosaniline Dyes
  • Sentinel Lymph Node Biopsy / methods*
  • Skin Neoplasms / mortality
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Survival Analysis

Substances

  • Coloring Agents
  • Radioisotopes
  • Rosaniline Dyes
  • iso-sulfan blue