Specific genetic markers of endurance performance and VO2max

Exerc Sport Sci Rev. 2001;29(1):15-9. doi: 10.1097/00003677-200101000-00004.

Abstract

Specific genetic markers of endurance performance and VO2max. Exerc. Sport Sci. Rev., Vol. 29, No. 1, pp 15-19, 2001. Recent advances have revolutionized genetic studies of quantitative traits. Mitochondrial DNA and creatine kinase variations may influence VO2max. Other data strongly suggest that angiotensin-converting enzyme genotype affects VO2max and endurance performance capacity, but the mechanisms are unclear. A recent genome-wide scan study also has provided candidate loci requiring further study.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Creatine Kinase / genetics*
  • Creatine Kinase / metabolism
  • Genetic Markers
  • Humans
  • Oxygen Consumption*
  • Peptidyl-Dipeptidase A / genetics*
  • Peptidyl-Dipeptidase A / metabolism
  • Physical Endurance / physiology*
  • Polymorphism, Genetic
  • Pulmonary Diffusing Capacity

Substances

  • Genetic Markers
  • Creatine Kinase
  • Peptidyl-Dipeptidase A