In vitro activities of linezolid against multiple Nocardia species

Antimicrob Agents Chemother. 2001 Apr;45(4):1295-7. doi: 10.1128/AAC.45.4.1295-1297.2001.

Abstract

Linezolid was tested by broth microdilution against 140 clinical Nocardia isolates belonging to seven species. The MIC at which 50% of the strains are inhibited (MIC50) and MIC90 for all species other than Nocardia farcinica were 2 and 4 microg/ml. Linezolid is the first antimicrobial agent demonstrated to be active against all Nocardia species.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetamides / pharmacology*
  • Anti-Bacterial Agents / pharmacology*
  • Linezolid
  • Microbial Sensitivity Tests
  • Nocardia / drug effects*
  • Oxazolidinones / pharmacology*
  • Species Specificity

Substances

  • Acetamides
  • Anti-Bacterial Agents
  • Oxazolidinones
  • Linezolid