Diabetes Screening in Canada (DIASCAN) Study: prevalence of undiagnosed diabetes and glucose intolerance in family physician offices

Diabetes Care. 2001 Jun;24(6):1038-43. doi: 10.2337/diacare.24.6.1038.

Abstract

Objective: To assess the prevalence of undiagnosed diabetes and glucose intolerance in individuals > or =40 years of age who contacted their family physician for routine care.

Research design and methods: The study used a stratified randomized selection of family physicians across Canada that was proportional to provincial and urban/rural populations based on Statistics Canada Census data (1996). Consecutive patients > or =40 years of age were screened for diabetes. If a casual fingerprick blood glucose was >5.5 mmol/l, the patient returned for a fasting venous blood glucose test. If the fasting blood glucose was 6.1-6.9 mmol/l, a 2-h 75-g post-glucose load venous blood glucose was obtained. Results of these tests were used to classify patients in diagnostic categories.

Results: Data were available for 9,042 patients. Previously undiagnosed diabetes was discovered in 2.2% of the patients, and new glucose intolerance was found in an additional 3.5% of patients. Overall, 16.4% of patients had previously known diabetes. The decrease in fasting plasma glucose criterion from 7.8 to 7.0 mmol/l resulted in a 2.2% versus a 1.6% prevalence of new diabetes. Several risk factors were reported in a significantly greater proportion of patients with new glucose intolerance and either new and known diabetes compared with the normal glucose tolerance group of patients.

Conclusions: Routine screening for diabetes by family physicians is justified in patients > or =40 years of age, given the finding of previously undiagnosed diabetes in 2.2% of these patients and newly diagnosed glucose intolerance in an additional 3.5% of these patients. Another 16.4% of primary care patients > or =40 years of age have known diabetes. This has important implications regarding health resources and physician education.

MeSH terms

  • Adult
  • Blood Glucose / analysis
  • Canada / epidemiology
  • Cholesterol, HDL / blood
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / epidemiology*
  • Diabetes, Gestational / epidemiology
  • Diagnostic Errors / statistics & numerical data*
  • False Negative Reactions
  • Family Practice*
  • Fasting
  • Female
  • Glucose Intolerance / diagnosis*
  • Glucose Intolerance / epidemiology*
  • Glucose Tolerance Test
  • Heart Diseases / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Male
  • Physicians, Family
  • Pregnancy
  • Random Allocation
  • Reproducibility of Results
  • Risk Factors
  • Rural Population
  • Triglycerides / blood
  • Urban Population

Substances

  • Blood Glucose
  • Cholesterol, HDL
  • Triglycerides