Soft tissue sarcoma--compliance with guidelines

Cancer. 2001 Jun 1;91(11):2186-95. doi: 10.1002/1097-0142(20010601)91:11<2186::aid-cncr1248>3.0.co;2-3.

Abstract

Background: Because soft tissue sarcomas (STS) are rare, guidelines for the diagnosis and treatment of patients with STS were developed. Because the diagnostic management is essential for definitive treatment, adherence to these guidelines is important.

Methods: Primary STS registered by the Comprehensive Cancer Center North-Netherlands from January 1989 to January 1996 were analyzed retrospectively with regard to adherence to the diagnostic guidelines. Urogenital, gastrointestinal STS, and Kaposi sarcomas were excluded.

Results: Three hundred fifty-one STS patients were analyzed. In the specialized center, 69% of patients were age < 60 years, whereas, in district hospitals, 63% of patients were age > 60 years. With increased age, referral to the center declined in a linear fashion. For all guidelines, adherence was significantly better in the center. In district hospitals, patient volume had no significant influence on compliance with the guidelines, except for the management of patients with STS > or = 3 cm. In district hospitals, where fewer than 15 patients were treated in the 7-year period, significantly more often, an inadequate biopsy or even no biopsy procedure was performed prior to resection.

Conclusions: In many aspects of the diagnostic process of STS, existing guidelines were not followed, especially in community hospitals. Adherence to all individual guidelines was significantly better in the specialized center. To improve compliance with future STS guidelines, appropriate guideline development, dissemination, and implementation programs should be developed. Concentration of patients with STS in a limited number of hospitals and intensified collaboration with specialized centers seem advisable. Special attention should be paid to older patients, who significantly more often were not referred to a specialized center.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Biopsy
  • Diagnosis, Differential
  • Female
  • Guideline Adherence*
  • Hospitals, Community
  • Humans
  • Male
  • Medical Audit
  • Middle Aged
  • Neoplasm Staging
  • Practice Guidelines as Topic*
  • Referral and Consultation
  • Retrospective Studies
  • Sarcoma / diagnosis*
  • Soft Tissue Neoplasms / diagnosis*