Candida dubliniensis in radiation-induced oropharyngeal candidiasis

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Jun;91(6):659-62. doi: 10.1067/moe.2001.112946.

Abstract

Candida dubliniensis is a recently described species that has been shown to cause oropharyngeal candidiasis in patients with HIV. We present a detailed evaluation of a patient undergoing head and neck radiation for oral cancer who developed oropharyngeal candidiasis from a mixed infection of C dubliniensis and Candida albicans. To our knowledge, this is the first described case of C dubliniensis contributing to oropharyngeal candidiasis in this patient population.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use
  • Candida / classification*
  • Candida / genetics
  • Candida / growth & development
  • Candida albicans / growth & development
  • Candidiasis / microbiology*
  • Candidiasis, Oral / microbiology*
  • Carcinoma, Squamous Cell / radiotherapy*
  • Carcinoma, Squamous Cell / secondary
  • Chromogenic Compounds
  • DNA, Fungal / analysis
  • Female
  • Fluconazole / administration & dosage
  • Fluconazole / therapeutic use
  • Head and Neck Neoplasms / radiotherapy*
  • Head and Neck Neoplasms / secondary
  • Humans
  • Karyotyping
  • Lymphatic Metastasis / radiotherapy
  • Mouth Neoplasms / radiotherapy*
  • Oropharynx / microbiology*
  • Pharyngeal Diseases / microbiology*
  • Radiation Injuries / microbiology*

Substances

  • Antifungal Agents
  • Chromogenic Compounds
  • DNA, Fungal
  • Fluconazole