Abstract
Two new sesquiterpenoids, 4,5-epoxy-13-methoxy-1(10)-germacren-12,6-olide and 4,5-epoxy-13-acetoxy-1(10)-germacren-12,6-olide, were isolated from the leaves of Magnolia grandiflora, together with six known compounds, 2alpha-hydroxy-dihydroparthenolide, parthenolide, costunolide, syringaresinol, (+) medioresinol and 6,7-dimethoxycoumarin. The structures of the new compounds were elucidated on the basis of spectroscopic methods and X-ray diffraction.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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China
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Drugs, Chinese Herbal / chemistry
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Magnetic Resonance Spectroscopy
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Magnoliaceae / chemistry*
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Molecular Structure
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Plant Leaves / chemistry
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Plants, Medicinal / chemistry
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes, Germacrane*
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X-Ray Diffraction
Substances
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4,5-epoxy-13-acetoxy-1(10)-germacren-12,6-olide
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4,5-epoxy-13-methoxy-1(10)-germacren-12,6-olide
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Drugs, Chinese Herbal
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Sesquiterpenes
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Sesquiterpenes, Germacrane