Asymmetric synthesis of carbocyclic pyrimidine nucleosides via pi-allylpalladium complex

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1367-70. doi: 10.1081/NCN-100002557.

Abstract

Racemic and enantiomerically pure carbocyclic pyrimidine nucleosides were synthesized efficiently by a convergent approach using Trost nucleophilic addition of pi-allylpalladium complexes.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Allyl Compounds / chemistry*
  • Organometallic Compounds / chemistry*
  • Palladium / chemistry*
  • Pyrimidine Nucleosides / chemical synthesis*
  • Stereoisomerism

Substances

  • Allyl Compounds
  • Organometallic Compounds
  • Pyrimidine Nucleosides
  • Palladium