Magnetic resonance imaging and magnetic resonance spectroscopy in dementias

J Geriatr Psychiatry Neurol. 2001 Fall;14(3):145-66. doi: 10.1177/089198870101400308.

Abstract

This article reviews recent studies of magnetic resonance imaging and magnetic resonance spectroscopy in dementia, including Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, idiopathic Parkinson's disease, Huntington's disease, and vascular dementia. Magnetic resonance imaging and magnetic resonance spectroscopy can detect structural alteration and biochemical abnormalities in the brain of demented subjects and may help in the differential diagnosis and early detection of affected individuals, monitoring disease progression, and evaluation of therapeutic effect.

Publication types

  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / metabolism
  • Amygdala / metabolism
  • Amygdala / pathology
  • Atrophy / metabolism
  • Atrophy / pathology
  • Brain / metabolism*
  • Brain / pathology*
  • Cognition Disorders / diagnosis
  • Corpus Callosum / metabolism
  • Corpus Callosum / pathology
  • Dementia / diagnosis*
  • Dementia / metabolism*
  • Dementia, Vascular / diagnosis
  • Dementia, Vascular / metabolism
  • Entorhinal Cortex / metabolism
  • Entorhinal Cortex / pathology
  • Frontal Lobe / metabolism
  • Frontal Lobe / pathology
  • Hippocampus / metabolism
  • Hippocampus / pathology
  • Humans
  • Huntington Disease / diagnosis
  • Huntington Disease / metabolism
  • Lewy Bodies / metabolism
  • Lewy Bodies / pathology
  • Magnetic Resonance Imaging*
  • Magnetic Resonance Spectroscopy*
  • Parkinson Disease / diagnosis
  • Parkinson Disease / metabolism
  • Temporal Lobe / metabolism
  • Temporal Lobe / pathology