Comparative performance of herpes simplex virus type 2-specific serologic assays from Meridian Diagnostics and MRL diagnostics

J A Ribes; M Hayes; A Smith; J L Winters; D J Baker

doi:10.1128/JCM.39.10.3740-3742.2001

Comparative performance of herpes simplex virus type 2-specific serologic assays from Meridian Diagnostics and MRL diagnostics

J Clin Microbiol. 2001 Oct;39(10):3740-2. doi: 10.1128/JCM.39.10.3740-3742.2001.

Authors

J A Ribes¹, M Hayes, A Smith, J L Winters, D J Baker

Affiliation

¹ Department of Clinical Laboratory Sciences, University of Kentucky, Lexington, Kentucky 40536-0298, USA. jaribes@uky.edu

Abstract

MRL Diagnostics and Meridian Diagnostics have recently designed herpes simplex virus type 2 (HSV-2)-specific enzyme immunoassays for HSV-2 antibody detection. Blood donor sera were assayed for HSV-2 antibodies by both methods. The sensitivity, specificity, and efficiency were 97.9, 95.4, and 95.9% for the MRL assay and 83.2, 98.2, and 95.5% for the Meridian assay, respectively.

Publication types

Comparative Study
Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Viral / blood*
Herpes Genitalis / diagnosis*
Herpes Genitalis / virology
Herpesvirus 2, Human / immunology*
Humans
Immunoenzyme Techniques / methods*
Reagent Kits, Diagnostic
Sensitivity and Specificity

Substances

Antibodies, Viral
Reagent Kits, Diagnostic