Morphological analysis of developmental changes in pontine noradrenergic neuronal groups in the neonatal rat

Brain Res. 2002 Jan 18;925(1):107-9. doi: 10.1016/s0006-8993(01)03256-5.

Abstract

We examined the morphological changes in two pontine noradrenergic neuronal groups, area A5 and the locus coeruleus (LC), in neonatal Sprague-Dawley rats between postnatal day 1 and day 10. The volume of the unilateral LC exhibited no significant developmental change. Meanwhile, the number of A5 neurones counted unilaterally was significantly larger on days 1-2 than on days 3-4 or day 10.

MeSH terms

  • Animals
  • Animals, Newborn
  • Cell Count
  • Locus Coeruleus / cytology*
  • Locus Coeruleus / growth & development*
  • Neurons / cytology
  • Norepinephrine / physiology*
  • Pons / cytology*
  • Pons / growth & development*
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Norepinephrine