Acquired haemophilia in South Australia: a case series

Intern Med J. 2001 Dec;31(9):556-9. doi: 10.1046/j.1445-5994.2001.00127.x.

Abstract

Of eight cases of acquired haemophilia presenting over an 8-year period, six received immunosuppressive treatment, five with cyclophosphamide, vincristine and prednisolone (CVP). Five patients (four on immunosuppressive treatment) entered remission, two patients died and one was lost to follow up. Initially, the remissions were only partial. The median duration until partial remission was 10 weeks (range 1-55 weeks) and until complete remission was 35 weeks (range 2-59 weeks). Partial remission may proceed to complete remission without further chemotherapy.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Hemophilia A / drug therapy*
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Middle Aged
  • Remission Induction
  • South Australia
  • Time Factors
  • Treatment Outcome

Substances

  • Immunosuppressive Agents