Computational methods for single-point and multipoint analysis of genetic variants associated with a simulated complex disorder in a general population

Genet Epidemiol. 2001:21 Suppl 1:S738-45. doi: 10.1002/gepi.2001.21.s1.s738.

Abstract

Several techniques for association analysis have been applied to simulated genetic data for a general population. We describe and compare the performance of three single-point methods and two multipoint approaches rooted in machine learning and data mining.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Artificial Intelligence
  • Genetic Predisposition to Disease / genetics*
  • Genetic Variation*
  • Genetics, Population*
  • Genotype
  • Humans
  • Linkage Disequilibrium
  • Models, Genetic*
  • Multivariate Analysis
  • Neural Networks, Computer