Dendrimer with rotaxane-like mechanical branching

Arkadij M Elizarov; Sheng-Hsien Chiu; Peter T Glink; J Fraser Stoddart

doi:10.1021/ol016928t

Dendrimer with rotaxane-like mechanical branching

Org Lett. 2002 Mar 7;4(5):679-82. doi: 10.1021/ol016928t.

Authors

Arkadij M Elizarov¹, Sheng-Hsien Chiu, Peter T Glink, J Fraser Stoddart

Affiliation

¹ Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, California 90095-1569, USA.

PMID: 11869100
DOI: 10.1021/ol016928t

Abstract

[reaction: see text] A dendrimer wherein the branching points are mechanical in nature has been synthesized. It contains two identical covalently linked bis-dendrons and a core unit fused to two rings that encircle the two bis-dendrons. A "threading-followed-by-stoppering" approach is used in the template-directed synthesis of a precursor bis[2]rotaxane, which undergoes stopper exchange four times to yield the dendrimer in which the two bis-dendrons act as stoppers within the two [2]rotaxane subunits.