Urokinase lysis for acute left subclavian artery thrombosis after placement of infusion catheter: report of two cases

Cardiovasc Intervent Radiol. 2002 Mar-Apr;25(2):141-3. doi: 10.1007/s00270-001-0108-5. Epub 2002 Feb 19.

Abstract

We present two cases of acute subclavian and/or axillary arterial occlusion after transaxillary catheterization with an implantable port for hepatic arterial infusion chemotherapy. They were successfully treated with thrombolytic therapy using intraarterial administration of urokinase without removal of the infusion catheter system. We consider that this treatment is suitable for managing acute thrombosis of the conduit artery after catheterization for hepatic arterial infusion chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / adverse effects
  • Arterial Occlusive Diseases / drug therapy*
  • Arterial Occlusive Diseases / etiology*
  • Catheterization, Peripheral
  • Follow-Up Studies
  • Humans
  • Infusions, Intra-Arterial / adverse effects*
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / drug therapy
  • Male
  • Middle Aged
  • Radiography
  • Risk Assessment
  • Subclavian Artery / diagnostic imaging
  • Subclavian Artery / drug effects
  • Thrombolytic Therapy / methods*
  • Treatment Outcome
  • Urokinase-Type Plasminogen Activator / therapeutic use*

Substances

  • Antineoplastic Agents
  • Urokinase-Type Plasminogen Activator