Synthesis of disubstituted cucurbit[6]uril and its rotaxane derivative

Hiroyuki Isobe; Sota Sato; Eiichi Nakamura

doi:10.1021/ol025749o

Synthesis of disubstituted cucurbit[6]uril and its rotaxane derivative

Org Lett. 2002 Apr 18;4(8):1287-9. doi: 10.1021/ol025749o.

Authors

Hiroyuki Isobe¹, Sota Sato, Eiichi Nakamura

Affiliation

¹ Department of Chemistry, The University of Tokyo, Bunkyo, Hongo, Tokyo 113-0033, Japan.

PMID: 11950344
DOI: 10.1021/ol025749o

Abstract

Synthesis of diphenyl cucurbit[6]uril (CB[6]) has been achieved via co-oligomerization of diphenyl glycoluril and unsubstituted glycoluril. The unsymmetrically substituted CB[6], Ph(2)CB[6], was further converted to a rotaxane incorporating bis(dinitrophenyl)spermine. [reaction: see text]

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bridged-Ring Compounds / chemical synthesis*
Imidazoles / chemical synthesis*
Indicators and Reagents
Magnetic Resonance Spectroscopy
Models, Molecular
Rotaxanes

Substances

Bridged-Ring Compounds
Imidazoles
Indicators and Reagents
Rotaxanes
cucurbit(6)uril