Intimin facilitates colonization by Escherichia coli O157:H7 in adult ruminants

Infect Immun. 2002 May;70(5):2704-7. doi: 10.1128/IAI.70.5.2704-2707.2002.

Abstract

We compared the magnitude and duration of fecal shedding of wild-type Escherichia coli O157:H7 to that of an isogenic intimin mutant in young adult cattle and sheep. In both ruminant species, wild-type E. coli O157:H7 was shed in greater numbers and for a longer duration than was the intimin mutant.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adhesins, Bacterial / physiology*
  • Animals
  • Carrier Proteins / physiology*
  • Cattle / microbiology*
  • Escherichia coli O157 / isolation & purification*
  • Escherichia coli Proteins*
  • Feces / microbiology*
  • Sheep / microbiology*

Substances

  • Adhesins, Bacterial
  • Carrier Proteins
  • Escherichia coli Proteins
  • eaeA protein, E coli