Circumcision in a combined factor V and factor VIII deficiency using desmopressin (DDAVP)

Turk J Pediatr. 2002 Apr-Jun;44(2):146-7.

Abstract

Combined factor V and VIII deficiency is a rare inherited autosomal recessive single gene disorder commonly seen in the Middle East. Although the factor levels are between 5-30%, several authors have reported that these patients are more prone to bleeding compared to those having an isolated factor deficiency with the same levels. We report an eight-year-old boy with factor V and VIII deficiency who underwent a successful circumcision using desmopressin (DDAVP).

Publication types

  • Case Reports

MeSH terms

  • Child
  • Circumcision, Male / adverse effects*
  • Deamino Arginine Vasopressin / therapeutic use*
  • Factor V Deficiency / complications*
  • Hemophilia A / complications*
  • Hemorrhage / etiology
  • Hemorrhage / prevention & control*
  • Hemostatics / therapeutic use*
  • Humans
  • Male
  • Mannose-Binding Lectins*
  • Membrane Proteins / genetics

Substances

  • Hemostatics
  • LMAN1 protein, human
  • Mannose-Binding Lectins
  • Membrane Proteins
  • Deamino Arginine Vasopressin