Glutathione S-transterased (GSTs) are a highly divergent gene family. They play important roles not only in many stress responses, but also in plant growth and development. To understand whether the GST can protect plant from the damage of ultra-violet (UV) radiation, a UV inducible GST gene was isolated from an Arabidopsis cDNA library. The plant expression vector containing the GST cDNA was constructed and transferred into Arabidopsis thaliana plants by the Agrobacterium-mediated vacuum method. Molecular genetic analyses showed that the overexpression of the UV inducible GST could increase the tolerance of the transgenic plants to UV radiation.