A clinical protocol for treatment of canine mammary tumors using encapsulated, cytochrome P450 synthesizing cells activating cyclophosphamide: a phase I/II study

J Mol Med (Berl). 2002 Sep;80(9):610-4. doi: 10.1007/s00109-002-0356-0. Epub 2002 Jun 28.

Authors

Stanislaw Winiarczyk¹, Zbigniew Gradski, Barbara Kosztolich, Cornelia Gabler, Gerhardt König, Matthias Renner, Robert M Saller, Heinrich Prosl, Brian Salmons, Walter H Günzburg, Johannes Hain

Affiliation

¹ Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, Agriculture University, Gleboka Street 30, 20612 Lublin, Poland.

PMID: 12226743
DOI: 10.1007/s00109-002-0356-0

No abstract available

MeSH terms

Animals
Antineoplastic Agents, Alkylating / therapeutic use*
Capsules
Cell Transplantation
Combined Modality Therapy
Cyclophosphamide / administration & dosage
Cyclophosphamide / pharmacokinetics
Cyclophosphamide / therapeutic use*
Cytochrome P-450 CYP2B1 / genetics*
Cytochrome P-450 CYP2B1 / metabolism
Dog Diseases / therapy*
Dogs
Female
Follow-Up Studies
Gene Expression
Genetic Therapy / methods*
Humans
Injections
Mammary Neoplasms, Animal / therapy*
Pilot Projects
Prodrugs / therapeutic use*
Transplantation, Heterologous
Treatment Outcome

Substances

Antineoplastic Agents, Alkylating
Capsules
Prodrugs
Cyclophosphamide
Cytochrome P-450 CYP2B1