Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 ( PSPLA1)

J Hum Genet. 2002;47(11):611-3. doi: 10.1007/s100380200093.

Abstract

We report the identification of nine DNA polymorphisms in PSPLA1 encoding phosphatidylserine-specific phospholipase A1. Because the gene product shares homology with triglyceride lipases, these polymorphisms may be useful in association studies with metabolic traits such as hypertriglyceridemia and related lipoprotein abnormalities, and will also provide tools for mapping studies of chromosome 3q13.13-13.2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Gene Frequency
  • Humans
  • Hypertriglyceridemia / genetics
  • Male
  • Molecular Sequence Data
  • Phospholipases A / genetics*
  • Phospholipases A1
  • Polymorphism, Genetic*
  • Triglycerides / blood
  • White People / genetics

Substances

  • Triglycerides
  • PLA1A protein, human
  • Phospholipases A
  • Phospholipases A1

Associated data

  • GENBANK/AF035268