Replacing the ascending aorta and aortic valve for acute prosthetic valve endocarditis: is using prosthetic material contraindicated?

Ann Thorac Surg. 2002 Nov;74(5):S1781-5; discussion S1792-9. doi: 10.1016/s0003-4975(02)04142-5.

Abstract

Background: The use of prosthetic material (rather than a homograft) for ascending aorta/aortic valve replacement (Bentall procedure) in cases of acute prosthetic valve endocarditis is controversial. We report favorable results using this technique almost exclusively (a homograft was used in only 3 patients with hematological problems) during a 12-year interval.

Methods: Twenty-eight patients (55 +/- 14 years; 22 male) underwent a Bentall procedure for acute prosthetic valve endocarditis between 1988 and 2000. Twenty-five patients had undergone previous aortic valve replacement (1 with concomitant mitral valve replacement, 4 with coronary artery bypass grafting), and 3 had had a previous Bentall operation. The median interval between initial surgery and reoperation was 13 months (range, 1 to 106). Sixty-eight percent of operations were urgent or emergencies. Ninety-three percent of patients had significant aortic regurgitation; complete annuloaortic dehiscence occurred in 71%, and in 57%, an abscess was found. Causative organisms were identified in 25 of 28 patients: Staphylococcus epidermidis (9), Staphylococcus aureus (7), Streptococcus viridans (6), Pseudomonas (2), and Legionella (1).

Results: Twenty-three patients had mechanical and 5 had biological valves implanted during the Bentall procedure. Hypothermic circulatory arrest was used in 64%. Hospital mortality was 11%: there was one intraoperative death, and two before discharge (one cardiac, one sepsis). Eighty-nine percent survived without stroke. During follow-up (median, 44.5 months; complete in 92%), 1 patient died of recurrent endocarditis at 4 months.

Conclusions: These results indicate that prosthetic root replacement may be superior to use of a homograft for acute aortic prosthetic valve endocarditis, with only a 4% incidence of recurrent endocarditis and reoperation.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aorta / transplantation*
  • Aortic Valve / transplantation*
  • Bioprosthesis
  • Blood Vessel Prosthesis*
  • Cause of Death
  • Contraindications
  • Endocarditis, Bacterial / mortality
  • Endocarditis, Bacterial / surgery*
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis*
  • Hospital Mortality
  • Humans
  • Male
  • Middle Aged
  • Prosthesis-Related Infections / mortality
  • Prosthesis-Related Infections / surgery*
  • Reoperation / methods
  • Reoperation / mortality
  • Survival Rate
  • Transplantation, Homologous