Nucleic acid components and their analogues: a novel and efficient method for the synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides from pyridine-2(1H)-thiones

Galal H Elgemeie; Mervat M El-Enany; Mohamed M Ismail; Eman K Ahmed

doi:10.1081/NCN-120014820

Nucleic acid components and their analogues: a novel and efficient method for the synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides from pyridine-2(1H)-thiones

Nucleosides Nucleotides Nucleic Acids. 2002 Jun-Jul;21(6-7):477-93. doi: 10.1081/NCN-120014820.

Authors

Galal H Elgemeie¹, Mervat M El-Enany, Mohamed M Ismail, Eman K Ahmed

Affiliation

¹ Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt. elegmei@hotmail.com

PMID: 12442965
DOI: 10.1081/NCN-120014820

Abstract

A novel synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides utilizing the reactions of heterocyclic substituted pyridine-2(1H)-thiones and alpha-bromoglucose or alpha-bromogalactose tetraacetate as starting components is described.

MeSH terms

2,2'-Dipyridyl / chemical synthesis
2,2'-Dipyridyl / chemistry*
Cycloparaffins / chemistry
Galactose / chemistry
Glucose / chemistry
Heterocyclic Compounds / chemical synthesis*
Heterocyclic Compounds / chemistry
Magnetic Resonance Spectroscopy
Nitriles / chemistry
Nitrogen / chemistry*
Thioglycosides / chemical synthesis*
Thiones / chemistry*

Substances

Cycloparaffins
Heterocyclic Compounds
Nitriles
Thioglycosides
Thiones
2,2'-Dipyridyl
Glucose
Nitrogen
Galactose