Atypical lipomatous tumour (lipoma-like well-differentiated liposarcoma) arising in a pulmonary hamartoma and clinically presenting with pneumothorax

Lung Cancer. 2003 Jan;39(1):103-6. doi: 10.1016/s0169-5002(02)00393-8.

Abstract

We document an uncommon variant of pulmonary hamartoma (PH), discovered in the left upper lobe of a 60-year-old man after an episode of pneumothorax, a unique clinical presentation for such an occurrence. The tumour showed a prominent leaf-like pattern and was mainly composed of mature fat with adipocytes of different size and scattered throughout lipoblasts and floret-like cells. A lobectomy was performed and more than 7 years after surgery the patient's course is still uneventful. This case represents an exceedingly rare example of an histologically malignant change in PH and bears a close clinicopathologic resemblance to atypical lipomatous tumours of soft tissues.

Publication types

  • Case Reports

MeSH terms

  • Hamartoma / complications
  • Hamartoma / pathology*
  • Humans
  • Liposarcoma / complications*
  • Liposarcoma / pathology*
  • Lung Neoplasms / complications*
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / surgery
  • Male
  • Middle Aged
  • Pneumothorax / complications*
  • Pneumothorax / pathology
  • Treatment Outcome