Arsenic speciation in the urine and hair of individuals exposed to airborne arsenic through coal-burning in Guizhou, PR China

Toxicol Lett. 2003 Jan 31;137(1-2):35-48. doi: 10.1016/s0378-4274(02)00379-x.

Abstract

The extent of exposure of residents of Changqing (Guizhou, PR China) to arsenic through coal-burning was investigated. Despite the low coal-arsenic content (56.3+/-42.5 mg As kg(-1)) when compared with coals collected at different location and times from the same province, more than 30% of the study subjects have shown symptoms of arsenicosis. Coal, urine, hair, and water samples were collected in mid-September 2001 and analysed for arsenic. The average urinary and hair-arsenic concentrations in the exposed subjects were 71.4+/-37.1 microg As g(-1) creatinine (control 41.6+/-12.1) and 7.99+/-8.16 mg kg(-1), respectively. A positive correlation between the hair and urinary-arsenic concentration (R(2)=0.601) was found. There was no significant difference between females and males for both urinary and hair-arsenic concentrations. Females were found to have a higher dimethylarsinic acid but lower percentages of inorganic arsenic and monomethylarsonic acid in their urine than males.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Air Pollution*
  • Arsenic / analysis*
  • Arsenic / urine
  • Arsenic Poisoning*
  • Arsenicals / analysis
  • Cacodylic Acid / analysis
  • China
  • Coal / analysis
  • Environmental Exposure*
  • Environmental Monitoring
  • Female
  • Hair / chemistry*
  • Humans
  • Inhalation Exposure
  • Male
  • Middle Aged
  • Power Plants
  • Water Supply / analysis

Substances

  • Arsenicals
  • Coal
  • Cacodylic Acid
  • monomethylarsonic acid
  • Arsenic