Not just any T cell receptor will do

Immunity. 2003 Jan;18(1):7-11. doi: 10.1016/s1074-7613(02)00517-4.

Abstract

Although our structural understanding of T cell recognition has rapidly evolved due to recent crystallographic results, the reality is that detailed answers to many of the most fundamental questions still remain elusive. In this issue, high-resolution insight into the phenomenon of TCR chain bias takes down another brick from the wall.

Publication types

  • Comment
  • Review

MeSH terms

  • Binding Sites
  • Complementarity Determining Regions
  • Histocompatibility Antigens Class I / chemistry
  • Humans
  • Macromolecular Substances
  • Models, Molecular
  • Receptors, Antigen, T-Cell / chemistry*
  • Receptors, Antigen, T-Cell / genetics
  • T-Lymphocytes / immunology

Substances

  • Complementarity Determining Regions
  • Histocompatibility Antigens Class I
  • Macromolecular Substances
  • Receptors, Antigen, T-Cell