Background: Recent reports raise the possibility that olanzapine, which commonly causes weight gain in non-eating-disordered subjects, assisted weight gain and mood during refeeding in anorexia nervosa (AN) patients.
Methods: Eighteen AN subjects who engaged in open treatment with olanzapine were retrospectively questioned about their response.
Results: Subjects reported a significant reduction in anxiety, difficulty eating, and core eating disorder symptoms after taking olanzapine.
Discussion: These data lend support to the possibility that olanzapine may be useful in AN patients.
Conclusion: A controlled trial is necessary to prove that olanzapine is efficacious.
Copyright 2003 by Wiley Periodicals, Inc.