Hydroxyurea-induced dermatomyositis-like eruption

J Am Acad Dermatol. 2003 Mar;48(3):439-41. doi: 10.1067/mjd.2003.74.

Abstract

Hydroxyurea is a cytotoxic chemotherapeutic agent used for myelodysplasia. The adverse cutaneous effects due to hydroxyurea include leg ulcers, hyperpigmentation of the skin and nails, a lichen planus-like eruption, lupus erythematosus, and a dermatomyositis-like eruption. We present a case of hydroxyurea-induced dermatomyositis-like eruption and review the features of this entity as previously reported.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Biopsy, Needle
  • Dermatomyositis / chemically induced*
  • Dermatomyositis / pathology*
  • Drug Eruptions / etiology
  • Drug Eruptions / pathology*
  • Female
  • Follow-Up Studies
  • Hand Dermatoses / chemically induced*
  • Hand Dermatoses / pathology
  • Humans
  • Immunohistochemistry
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy*
  • Risk Assessment