[Noma in HIV-infected adults]

Ann Dermatol Venereol. 2003 Feb;130(2 Pt 1):199-201.
[Article in French]

Abstract

Introduction: Noma is a necrotic stomatitis, frequent in undernourished children in tropical countries. Its occurrence in adults is extremely rare and has recently been described during AIDS. We report two new cases.

Observations: The first patient, a 37 year-old farmer, consulted for a mutilating ulcer of the commissure of the right lip. The second patient, a 25 year-old woman, consulted for an ulcerating and necrotic tumefaction of the left cheek. Anamnesis reconstructed the chronology of the lesions and a cutaneous biopsy revealed non-specific ulcers. The status of health of both patients was poor and they both exhibited positive HIV serology.

Discussion: The diagnosis of noma is easy and based on clinical manifestations. The characteristic aspect is that of a mutilating ulcer of the face with conventional progression: tumefaction, followed by ulceration and finally elimination necrosis. This disease predominates in children. Its discovery in adults is a sign of poor prognosis because it may reveal an HIV infection at the AIDS stage.

Conclusion: It is important to draw the attention of practitioners on the interest of performing HIV serology when confronted with an adult exhibiting a noma, and to evoke a noma when confronted with a tumefaction of the face rapidly progressing towards necrosis.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Age Factors
  • Female
  • HIV Infections / complications*
  • Humans
  • Male
  • Noma / pathology
  • Noma / virology*
  • Oral Ulcer / etiology
  • Prognosis