Low body weight and its association with bone health and pubertal maturation in Chinese girls

Eur J Clin Nutr. 2003 May;57(5):693-700. doi: 10.1038/sj.ejcn.1601599.

Abstract

Objective: To investigate the prevalence of low body weight in Beijing pubertal girls and to establish the cut-off for body mass index (BMI) for underweight for Chinese pubertal girls.

Design: Cross-sectional study.

Setting: Three socioeconomic areas (rural, suburban and urban) in Beijing, China.

Subjects: Random sample of 1214 adolescent girls aged 12-14 y from 13 middle schools.

Results: Using a modified Chinese reference, the rate of low body weight (BMI<18) was 32.2% (95% CI 29.6-34.8%). Compared with desirable weight girls (BMI=18-21), girls with low body weight had a lower bone age, delayed breast and pubic hair development, a lower rate of menarche, lower distal one-third radius and ulna bone mineral content (BMC), bone mineral density and bone width. Logistic regression showed that BMI was one of the predictors of one-third ulna BMC after adjustment for confounding variables. When comparing BMI<18 vs BMI=18-21, the risk of BMC being less than the median increased by 82% (odds ratio 1.82, 95% CI 1.06-3.13). Thinness and stunting rates assessed by WHO recommended cut-offs are also reported.

Conclusions: High prevalence of low body weight (BMI<18) was found to be a major health problem among Beijing pubertal girls. BMI<18 is confirmed as the cut-off for delayed general growth and development for Chinese girls and for screening girls at risk of lower bone mineral status.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Body Mass Index
  • Body Weight*
  • Bone Density*
  • Child
  • China
  • Female
  • Humans
  • Logistic Models
  • Menarche
  • Nutritional Status
  • Puberty*
  • Radius
  • Reference Values
  • Thinness*
  • Ulna
  • World Health Organization