[Study on HPLC fingerprint of the triterpene acids in Poria cocos]

Gang Ding; Zhen-zhong Wang; Chen-feng Zhang; Long-sheng Sheng

[Study on HPLC fingerprint of the triterpene acids in Poria cocos]

Zhongguo Zhong Yao Za Zhi. 2002 Oct;27(10):756-8.

[Article in Chinese]

Authors

Gang Ding¹, Zhen-zhong Wang, Chen-feng Zhang, Long-sheng Sheng

Affiliation

¹ Center for Instrumental Analysis, China Pharmaceutical University, Nanjing 210009, Jiangsu, China. dingg2000@mail.china.com

PMID: 12776555

Abstract

Objective: To establish a method for HPLC fingerprint determination of the triterpene acids in Poria cocos.

Method: RP-HPLC, linear gradient elution and LC/MS, etc. were used to optimize the fingerprint determination method, and identify the main peaks in the HPLC fingerprint.

Result: A preferable method for HPLC fingerprint determination of the triterpene acids in P. cocos was established, and 9 peaks in the HPLC fingerprint were identified.

Conclusion: A general acquaintance of the triterpene acids in P. cocos can be obtained by using the preferable HPLC fingerprint determination method, which is useful for quality evaluation of the crud drug of P. cocos.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, High Pressure Liquid / methods
Polyporales / chemistry*
Triterpenes / analysis*
Triterpenes / classification

Substances

Triterpenes